In speaking of the reasons for the appearance of semantics, certain writers note the following three problems the solution of which demanded semantic analysis: 1) the problem of antinomies; 2) the problem of refining and explaining the basic concepts of formalized logic and mathematics; and 3) the problem of the complete formalization of logic.

The book deals with the notion of Downward Causation from a wide array of perspectives, including physics, biology, psychology, social science, communication studies, text theory, and philosophy. The book includes proponents as well as opponents discussing the validity of the notion.

An interrogation of the term 'theory' from the perspective of linguistic discourse Zima offers a new definition of theory from a cultural and sociological perspective, with a view to encountering heterogenerous points of view in critical dialogue.

Presents an original theoretical system to explain and contrast modernism and postmodernism.

Clinical trials are essential to establish the safety and efficacy of investigational products, contributing to risk/benefit assessments that ultimately determine whether these products meet the criteria for market authorisation. Clinical trials are also an important source of revenue and expertise generation for countries in which they are conducted. In developing countries, they represent substantial foreign direct investment. In spite of the substantial capital input that clinical trials require, the issue of funding post-trial access to beneficial therapies remains contentious, especially in (...) resource-limited settings. In this article, we explore this situation and propose mechanisms to establish ‘win-win’ situations where both patients and clinical trial sponsors derive benefit from post-trial access programmes in low- and middle-income countries. (shrink)

J. T. Hooker argues that at Il. 24.649 πικερτομων must mean ‘taunting’ and, since ‘taunting’ makes no sense, that πικερτομων must have entered our Iliad at this point from a version of the Iliad slightly different from ours in which it did make sense. I wish to argue that πικερτομων has a meaning different from ‘taunting’, which makes good sense of this, and every other, context.